The Evidentiary Backbone for Jazz’s Global Growth Strategy
Accelerate value demonstration for drugs in the Oncology pipeline. Move beyond fragmented claims with a unified, research-grade RWE co-pilot designed for regulatory-standard outcomes and AI-driven evidence generation.
The Challenge
Scaling Evidence with Integrity in a Competitive Data Landscape
The Transparency Barrier
Relying on legacy data aggregators often results in opaque analytics that lack the “glass-box” transparency required for successful HTA submissions and ICER reviews.
Fragmented Claims Data
Jazz requires more than a simple data feed; it needs to solve for persistent gaps in patient enrollment and fragmented care journeys that can bias outcomes research.
Standard claims often suffer from incomplete adjudication and missing cost fields, making it difficult to generate the accurate Budget Impact Analyses (BIA) needed for high-stakes launches.
Rigor & Reproducibility
As evidence requirements for brands like Epidiolex and zanidatamab escalate, Jazz must move beyond manual query cycles toward an architecture that supports auditable, reproducible statistical code.
Solving with Komodo
Driving Clinical and Economic Alpha Across the Life Cycle
Precise Longitudinal Outcomes
Utilize a standardized 45-day gap rule to distinguish true treatment gaps from insurance switches, ensuring accurate real-world adherence and persistence modeling.

External Control Arm (ECA) Development:
Construct retrospective cohorts for oncology pipeline assets using the Healthcare Map™ and MapEnhance, integrating mortality and EMR data to contextualize trial results.

Regulatory-Grade HCRU:
Perform high-fidelity Healthcare Resource Utilization (HCRU) analyses with a 95%+ cost fill rate, ensuring budget impact models (BIA) are based on real-world reimbursement logic rather than raw, incomplete claims.

Enterprise AI Integration:
Embed Marmot™ into the Jazz AI Council roadmap to automate descriptive statistics and literature synthesis while maintaining full visible code (SQL/R) transparency.
The Komodo Impact
Transformative speed-to-insights with purpose-built AI, fueled by the industry’s most comprehensive data foundation, without compromising rigor.
Rapid Evidence Cycles
Reduce data integration and cleaning timelines by 4–9 months through pre-integrated specialty data and unified visit consolidation.
Enterprise Value Alignment
A single, hardened MSA/DPA and security framework that services Commercial, HEOR, Medical Affairs, and Clinical Development.
Publication-Ready Transparency
Every analytical step is reproducible and auditable, supporting the 375+ peer-reviewed studies already published using Komodo data.
Resources
Read more about how Komodo’s robust product suite can help you unlock your team’s expertise and accelerate decision-making across the enterprise.
AI Reliability Guide
Guide
Komodo Health’s HEOR Methodology
White Paper
How Marmot Delivers Enterprise Wide ROI
Perspectives
Gain Your Velocity Advantage
It starts with the right insights. Move beyond legacy data silos and experience a higher evidentiary standard for the Jazz portfolio. Supercharge your RWE strategy with the platform built for the future of Health Economics.